NFL Sunday Preview, Odds & Best Bets (Week 13): Rams Look to Stop Skid While Chiefs Eye Control of AFC West

The best day of the week, at least if you’re into NFL betting, is here. We have a dozen games to take in on this fine Sunday, and all of them are meaningful matchups for division title races and the NFL playoff picture, in some way.

The biggest game of Week 13 is tomorrow night as the Buffalo Bills host the New England Patriots. That game is a must-win game for the Bills as it is, but the right series of results today will only further decrease their margin for error tomorrow and the remainder of the season.

While Bills futures are looking a bit shaky right now thanks to the Patriots’ surge and the number of teams in the AFC wild-card picture that can still edge them out at this point, the same can’t be said for the Chiefs. When the Chiefs were 3-4 and Patrick Mahomes was being far too generous to opposing defenses, the outlook was not so positive. Four wins in a row and a lot of chaos around the AFC later, the Chiefs are once again the betting favorite to win the AFC. In tonight’s Sunday Night Football matchup, the Chiefs could take a step toward yet another AFC West crown with a win over the rival Broncos.

Let’s take a look at the NFL betting odds and top betting picks for that matchup and the other 11 games on today’s NFL slate.

NFL Schedule for Sunday, December 5, 2021

Tampa Bay Buccaneers (8-3) vs Atlanta Falcons (5-6), FOX, 1:00 p.m. ET

Arizona Cardinals (9-2) vs Chicago Bears (4-7), FOX, 1:00 p.m. ET

Los Angeles Chargers (6-5) vs Cincinnati Bengals (7-4), CBS, 1:00 p.m. ET

Minnesota Vikings (5-6) vs Detroit Lions (0-10-1), CBS, 1:00 p.m. ET

New York Giants (4-7) vs Miami Dolphins (5-7), FOX, 1:00 p.m. ET

Philadelphia Eagles (5-7) vs New York Jets (3-8), CBS, 1:00 p.m. ET

Indianapolis Colts (6-6) vs Houston Texans (2-9), CBS, 1:00 p.m. ET

Washington Football Team (5-6) vs Las Vegas Raiders (6-5), FOX, 4:05 p.m. ET

Jacksonville Jaguars (2-9) vs Los Angeles Rams (7-4), FOX, 4:05 p.m. ET

Baltimore Ravens (8-3) vs Pittsburgh Steelers (5-5-1), CBS, 4:25 p.m. ET

San Francisco 49ers (6-5) vs Seattle Seahawks (3-8), CBS, 4:25 p.m. ET

Denver Broncos (6-5) vs Kansas City Chiefs (7-4), 8:20 p.m. ET

NFL Betting Odds & Picks for Sunday, December 5, 2021

• Tampa Bay Buccaneers vs Atlanta Falcons
• Arizona Cardinals vs Chicago Bears
• Los Angeles Chargers vs Cincinnati Bengals
• Minnesota Vikings vs Detroit Lions
• New York Giants vs Miami Dolphins
• Philadelphia Eagles vs New York Jets
• Indianapolis Colts vs Houston Texans
• Washington Football Team vs Las Vegas Raiders
• Jacksonville Jaguars vs Los Angeles Rams
• Baltimore Ravens vs Pittsburgh Steelers
• San Francisco 49ers vs Seattle Seahawks
• Denver Broncos vs Kansas City Chiefs

NFL betting odds listed below are via BetOnline Sportsbook as of Sunday, December 5, 2021 at 11:50 a.m. ET. To compare NFL game odds from several top online sportsbooks, check out our NFL odds.

Betting News offers aggregated NFL picks for every NFL matchup each week. Below, we list the top pick(s) for each matchup. In cases where the moneyline is the top pick percentagewise but provides little to no betting value (as a single straight bet), we list the best option among the other options.

NFL Betting Picks: Week 13

Betting News aggregates our betting picks from trusted sports betting industry sources. Along with NFL picks for every NFL matchup, we also offer MLB picks, NBA picks, and NHL picks.

Tampa Bay Buccaneers vs Atlanta Falcons NFL Betting Odds & Picks

• Spread: Tampa Bay Buccaneers -10.5 (-114), Atlanta Falcons +10.5 (-106)
• Total: OVER 50.5 (-112), UNDER 50.5 (-108)
• Moneyline: Tampa Bay Buccaneers -510, Atlanta Falcons +390

Top Bucs vs Falcons Betting Pick: Falcons +10.5 (100 percent)

Bucs vs Falcons Matchup: NFL Betting Picks, Odds, Stats & More

Arizona Cardinals vs Chicago Bears NFL Betting Odds & Picks

• Spread: Arizona Cardinals -7.5 (-118), Chicago Bears +7.5 (-104)
• Total: OVER 42 (-114), UNDER 42 (-106)
• Moneyline: Arizona Cardinals -370, Chicago Bears +300

Top Cardinals vs Bears Betting Picks: Cardinals -7.5 (67 percent) & OVER 42.5 (67 percent)

Cardinals vs Bears Matchup: NFL Betting Picks, Odds, Stats & More

Los Angeles Chargers vs Cincinnati Bengals NFL Betting Odds & Picks

• Spread: Los Angeles Chargers +3 (-115), Cincinnati Bengals -3 (-105)
• Total: OVER 49.5 (-110), UNDER 49.5 (-110)
• Moneyline: Los Angeles Chargers +124, Cincinnati Bengals -146

Top Chargers vs Bengals Betting Picks: Bengals -3 (100 percent) & Bengals ML (100 percent)

Chargers vs Bengals Matchup: NFL Betting Picks, Odds, Stats & More

Minnesota Vikings vs Detroit Lions NFL Betting Odds & Picks

• Spread: Minnesota Vikings -7 (-114), Detroit Lions +7 (-106)
• Total: OVER 47.5 (-110), UNDER 47.5 (-110)
• Moneyline: Minnesota Vikings -310, Detroit Lions +250

Top Vikings vs Lions Betting Picks: Lions +7 (67 percent) & OVER 46.5 (67 percent)

Vikings vs Lions Matchup: NFL Betting Picks, Odds, Stats & More

New York Giants vs Miami Dolphins NFL Betting Odds & Picks

• Spread: New York Giants +6 (-110), Miami Dolphins -6 (-110)
• Total: OVER 40 (-112), UNDER 40 (-108)
• Moneyline: New York Giants +220, Miami Dolphins -270

Top Giants vs Dolphins Betting Picks: Giants +6.5 (67 percent) & UNDER 40 (67 percent)

Giants vs Dolphins Matchup: NFL Betting Picks, Odds, Stats & More

Philadelphia Eagles vs New York Jets NFL Betting Odds & Picks

• Spread: Philadelphia Eagles -5.5 (-110), New York Jets +5.5 (-110)
• Total: OVER 44.5 (-110), UNDER 44.5 (-110)
• Moneyline: Philadelphia Eagles -225, New York Jets +188

Top Eagles vs Jets Betting Pick: OVER 44.5 (100 percent)

Eagles vs Jets Matchup: NFL Betting Picks, Odds, Stats & More

Indianapolis Colts vs Houston Texans NFL Betting Odds & Picks

• Spread: Indianapolis Colts -10 (-110), Houston Texans +10 (-110)
• Total: OVER 45.5 (-110), UNDER 45.5 (-110)
• Moneyline: Indianapolis Colts -450, Houston Texans +350

Top Colts vs Texans Betting Pick: UNDER 45.5 (100 percent)

Colts vs Texans Matchup: NFL Betting Picks, Odds, Stats & More

Washington Football Team vs Las Vegas Raiders NFL Betting Odds & Picks

• Spread: Washington Football Team +1.5 (-110), Las Vegas Raiders -1.5 (-110)
• Total: OVER 48 (-110), UNDER 48 (-110)
• Moneyline: Washington Football Team +106, Las Vegas Raiders -124

Top WFT vs Raiders Betting Pick: Raiders ML (100 percent)

WFT vs Raiders Matchup: NFL Betting Picks, Odds, Stats & More

Jacksonville Jaguars vs Los Angeles Rams NFL Betting Odds & Picks

• Spread: Jacksonville Jaguars +13 (-110), Los Angeles Rams -13 (-110)
• Total: OVER 48 (-110), UNDER 48 (-110)
• Moneyline: Jacksonville Jaguars +530, Los Angeles Rams -750

Top Jaguars vs Rams Betting Picks: Rams -13 (67 percent) & OVER 48 (67 percent)

Jaguars vs Rams Matchup: NFL Betting Picks, Odds, Stats & More

Baltimore Ravens vs Pittsburgh Steelers NFL Betting Odds & Picks

• Spread: Baltimore Ravens -4 (-110), Pittsburgh Steelers +4 (-110)
• Total: OVER 44 (-114), UNDER 44 (-106)
• Moneyline: Baltimore Ravens -200, Pittsburgh Steelers +168

Top Ravens vs Steelers Betting Picks: Ravens -4 (67 percent) & UNDER 44.5 (67 percent)

Ravens vs Steelers Matchup: NFL Betting Picks, Odds, Stats & More

San Francisco 49ers vs Seattle Seahawks NFL Betting Odds & Picks

• Spread: San Francisco -3 (-108), Seattle Seahawks +3 (-112)
• Total: OVER 45 (-110), UNDER 45 (-110)
• Moneyline: San Francisco 49ers -154, Seattle Seahawks +130

Top 49ers vs Seahawks Betting Picks: 49ers ML (67 percent) & OVER 45 (67 percent)

49ers vs Seahawks Matchup: NFL Betting Picks, Odds, Stats & More

Denver Broncos vs Kansas City Chiefs NFL Betting Odds & Picks

• Spread: Denver Broncos +8.5 (-110), Kansas City Chiefs -8.5 (-110)
• Total: OVER 46.5 (-110), UNDER 46.5 (-110)
• Moneyline: Denver Broncos +310, Kansas City Chiefs -390

Top Broncos vs Chiefs Betting Pick: UNDER 46.5 (100 percent)

Broncos vs Chiefs Matchup: NFL Betting Picks, Odds, Stats & More