Big 12 Tournament, Iowa State vs BYU: NCAA Basketball Best Bets

The Big 12 Tournament is underway, and the Iowa State Cyclones ended Cincinnati’s hopes at the making the Big Dance. However, now they have a rematch against a team that already got the best of them this season. The 5th seeded Cyclones take on the 4th seeded BYU Cougars in the Big 12 Quarterfinals.

Like I said, these teams already played, and the Cougars were able to take down the Cyclones at Hilton Coliseum. That is no small feat. Despite Iowa State finally being full strength, the Cougars came into Ames, took them to double overtime and eventually took beat them at home.

But in the Big 12 tournament, in what is practically going to be a second home game for Iowa State, it will take even more for BYU to come out on top.

Iowa State Cyclones vs BYU Cougars: Big 12 Quarterfinals

Matchup Information – Iowa State vs BYU

• Venue & Location: T-Mobile Center (Kansas City, MO)
• Date: Thursday, March 13th, 2025
• Tip Off: 12:30pm Eastern
• Broadcast: ESPN2

Betting Odds

Odds courtesy of BetOnline, an industry leader in the sports betting world. Sign up today with promo code BNEWS for a 50% deposit bonus and $10 instantly in your account!

Spread

• Iowa State -3.5 (-110)
• BYU +3.5 (-110)

Total

• Over 146.5 (-105)
• Under 146.5 (-115)

Cyclones Looking for 2nd Straight Big 12 Tournament Title

The Iowa State Cyclones are no secret to playing well in this tournament. Other than Kansas, they have the most titles amongst Big 12 teams, and are the defending champions. In this revenge spot which is basically at home, I certainly lean with the Cyclones in this match.

Their defense is one of the best in the country, and they held Cincy to just 32.8% from the field, allowing  only 56 points. Iowa State forces plenty of turnovers, they get to the free throw line, and they now have plenty of scoring options from the outside. I trust this team to come well prepared to this second matchup, and focus exclusively on the defensive side of things.

Iowa State Cyclones vs BYU Cougars Best Bets

Iowa State vs BYU Prediction: Iowa State Wins & Covers, Over 146.5

Best Bets: Iowa State -3.5 (-110) BetOnline

You get the idea. This BYU offense is the best in the conference, but again, they already got the best of Iowa State. After beating the Cyclones in Ames, what more does BYU have to improve?

Iowa State has been playing that loss over and over in their heads, yearning for the chance to take them down a second time. BYU dominated the first half of the matchup, but then Iowa State scored 44 in the 2nd half to force double overtime, only to come up short.

The Cyclones have a fantastic head coach, and he is more than capable of making the adjustments needed to pull out a win in the Big 12 Tournament. The Cougars may have gotten the double bye, but Iowa State will be getting the last laugh after beating BYU when it matters.

Still Didn’t Get Your NCAA Basketball Fix?

Here at Betting News, we offer Free Expert Picks for every major sports league. We also host daily streams on our Twitch Channel with our best bets, as well as sweat out games on Playback! Be sure to tune into everything we have going on at our Youtube, TikTok, and X pages as well.

For more College Hoops action, check out these pages below.

• NCAA Basketball Expert Picks
• College Hoops Betting Guide
• College Basketball Championship Odds
• March Madness Bracket Projections

Check Out All of Our Resources at Betting News