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Thursday Night Football: 49ers vs. Seahawks | Odds & Best Bets

Written by: Varun Sharma

Last Updated:

Read Time: 6 minutes

Thursday Night Football: 49ers vs. Seahawks | Predictions & Best Bets

nfl

Thursday, Oct 107:15pm ET

San Francisco 49ers Odds

Spread

Total

Moneyline

-5.5

-143

-111o

-360

Seattle Seahawks Odds

Spread

Total

Moneyline

+5.5

+115

-115u

+280

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See Picks & Statistics For The Game

We’re now a third of the way through the 2024/2024 NFL Season and it’s been a wild ride, to say the least. Both the Seahawks and Niners are coming off brutal losses to the Giants and Cardinals, respectively.

Both teams need to figure it out and now with their first divisional matchup on the horizon, there’s no better time than the present.

Here are our best bets for the 49ers vs. Seahawks!

- George Kittle o48.5 Receing Yards (-117) via BetOnline
- Tyler Lockett o45.5 Receiving Yard (-115) via BetOnline

49ers @ Seahawks Game Information

Matchup Information

Location: Lumen Field; Seattle, Washington
Date: Thursday, October 10th, 2024
Kickoff: 8:15 PM EST

Quarterback Matchup

San Francisco 49ers: Brock Purdy (2-3; 2024 – 274.8 YPG | 6 TD | 4 INT)
Seattle Seahawks: Geno Smith (3-2; 2024 – 293.2 YPG | 5 TD | 4 INT)

Betting Odds

Odds via BetOnline, an industry leader in the sports betting world.

Run Line

San Francisco 49ers -3.5 (-104)
Seattle Seahawks +3.5 (-116)

Money Line

San Francisco 49ers (-190)
Seattle Seahawks (+165)

Total

Over 49 (-109)
Under 49 (-111)

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49ers @ Seahawks Analysis & Breakdown

The Niners and the Seahawks entered Week5 as two of the biggest favorites on the board and both fell to much lesser teams. The Niners now sit at 2-3 on the year, with losses to the Vikings, Rams and Cardinals.

San Francisco’s coming up on their third divisional game of the first six weeks and have now lost 2 of the 3 so far. If the Niners find a way to lose this game, they may seal their post-season fate before we’re halfway through the season.

The Seahawks came out of the gates firing. They began the season 3-0 and it looked like Geno Smith might really be the answer.

Smith’s averaging 293.8 passing yards per game, he’s thrown 5 touchdowns, 4 interceptions and has yet to throw multiple touchdowns in a single game this year.

Seattle’s lost back to back games, both games by more than a touchdown.

George Kittle o48.5 Receiving Yards (-117) via BetOnline – Get a $500 WELCOME BONUS

It’s tough to bet players nursing injuries in the NFL, especially when coming off a short week and playing on Thursday Night Football. Kittle’s currently nursing a bit of a rib injury but he played through it in Week 5.

Kittle played 58 of the 49ers 64 offensive snaps, he logged 8 catches on 12 targets and recorded 1 touchdown with 64 receiving yards. George has quickly become one of Purdy’s favorite targets; he leads all offensive skill positions (besides Purdy) in snaps (87%).

Purdy’s targeted Kittle 29 times in their 4 games together this year, with Kittle seeing a 25% target share in these 4 games; that target share jumps to 27.3% over his L3 games.

He’s scored 3 touchdowns this year, all 3 came over the last 3 weeks. Kittle’s been great against Seattle in his career, averaging 62.5 receiving yards per game on an average of 6.5 targets.

Those numbers jump to 71.6 yards per game with 4 of his 5 touchdowns coming IN Seattle.

With the Niners so beat up, desperate for a win, look for Kittle to make waves and do whatever it takes to help San Francisco secure a win.

George Kittle o48.5 Receiving Yards (-117) via BetOnline

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Tyler Lockett o45.5 Receiving Yards (-115) via BetOnline – Get a $500 WELCOME BONUS

Walk with me, it’s 2024 and we’re betting on Tyler Lockett. He currently sits third in targets for the Seattle Seahawks, behind both DK Metcalf and Jaxon Smith-Njigba; mainly because of a bad Week 2 where he saw just 2 targets.

Outside of Week 2, Lockett leads the team in targets, receptions and 2nd in receiving yards. This week he lines up against the 49ers, a team that’s been allowing less than 200 passing yards per game.

San Francisco’s sitting at 2-3 on the year and somehow haven’t even entered the toughest part of their schedule. Outside of Justin Jefferson in Week 1, the Niners have faced the Rams without Kupp/Nacua, the Cardinals, the Patriots, and the dysfunctional Jets.

They’ve yet to be really tested through the air and this week they face off with Geno Smith, the guy who’s averaging just under 300 passing yards per game.

Geno’s been one of the biggest reasons the Seahawks lead the division, and if they hope to stay there, they’ll need him to step up once again; that’s why we’re going with one of his favorite targets, Tyler Lockett.

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Tyler Lockett o45.5 Receiving Yards (-115) via BetOnline

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To Recap, NFL Bets for October 10th, 2024:

In the 49ers vs. Seahawks game on Sunday, we’re rolling with 2 plays. George Kittle o48.5 Receiving Yards (-114), and Tyler Lockett o45.5 Receiving Yards (-115).