Cleveland Guardians vs. New York Yankees MLB Picks and Predictions: June 3, 2026

Nate Hornung

Written by: Nate Hornung

Published: Wed Jun 03, 2026, 10:40 am ET

Read Time: 5 minutes

Will Gerrit Cole continue to shove tonight at home against the Cleveland Guardians? Guardians Yankees Picks

mlb

Cleveland Guardians logo
Today7:05 pm ET
New York Yankees logo

Cleveland Guardians
Odds

Spread

Total

Moneyline

+1.5

-155

7

-124u

+140

New York Yankees
Odds

Spread

Total

Moneyline

-1.5

145

7

+105o

-149

See Picks & Statistics For The Game

The Cleveland Guardians and New York Yankees met for the first time of the year last night, where the visitors upset their hosts, winning 9-4. This gave the Guardians a 2.5 game lead over the Chicago White Sox in the terrible AL Central, while the Yankees are still a single game behind the Tampa Bay Rays in the AL East. There is still plenty of baseball left to be played this season, but both will want to keep themselves at or near the top of the standings. Let's check out our favorite MLB picks for tonight's contest.

Check out the best odds on the market at our top online sportsbooks.

Cleveland Guardians vs. New York Yankees MLB Betting Insights

Jose Ramirez and the Guardians are looking for a second straight win on the road against the New York Yankees tonight - Guardians Yankees Picks

Jose Ramirez and the Guardians are looking for a second straight win on the road against the New York Yankees tonight

Both ball clubs are tossing out righties tonight, who have had very good seasons. Gavin Williams gets the nod for the Guardians and he brings an 8-3 record into tonight's contest. Williams is top 20 in the MLB in both ERA and WHIP this season, but admittedly his splits get a little worse away from home. Not drastically, but to the point where it is worth noting.

As for Gerrit Cole, he is shoving early on. Now, he's only made two starts this season, so it's an incredibly small sample size. But the man has yet to allow a run this year, has lasted at least six innings in both outings, and has 12 total strikeouts as well, just under one per inning. In his most recent start, Cole struck out 10 batters without a single walk, giving up just four hits in 6.2 scoreless innings. Will that continue tonight at home?

Matchup Information – Guardians vs. Yankees – June 3

  • Venue & Location: Yankee Stadium (Bronx, NY)
  • Date: Wednesday, June 3, 2026
  • First Pitch: 7:05 p.m. Eastern
  • Broadcast: Prime Video

Guardians vs. Yankees Pitching Matchup

  • Cleveland Guardians: RHP Gavin Williams (8-3, 3.07 ERA, 1.09 WHIP)
  • New York Yankees: RHP Gerrit Cole (1-0, 0.00 ERA, 0.71 WHIP)

Guardians vs. Yankees Betting Odds

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Run Line

  • Guardians +1.5 (-170)
  • Yankees -1.5 (+145)

Moneyline

  • Guardians +128
  • Yankees -153

Total

  • Over 7 (-120)
  • Under 7 (+100)
Click for more MLB Picks

Cleveland Guardians vs. New York Yankees MLB Picks

Ben Rice and the Yankees lost last night to the Guardians. Will they bounce back with a win at home tonight? Yankees Guardians Picks

Ben Rice and the Yankees lost last night to the Guardians. Will they bounce back with a win at home tonight?

Guardians vs. Yankees Prediction: Yankees Win and Cover, Under 7

Best Bet: Yankees F5 -0.5 (+100) Lucky Rebel Sportsbook

I don't hate backing the Yankees to cover the full game run line in this matchup, but I also lean with the under. Therefore, it doesn't make much sense to back them to win by two if there are only going to be five total runs scored (hypothetically). Instead, we will take the Yankees to start off hot, and earn at least one more run off of Williams than the Guardians do off Cole.

We saw nine of the 13 total runs scored within the first five innings last night, four of which came from New York. I have plenty of faith in the Yankees being able to rip against Williams. In his last road start, he pitched eight scoreless innings and allowed just five hits with 11 strikeouts against the Phillies. But in his two road starts prior to that, he allowed five runs to the Kansas City Royals and six to the Toronto Blue Jays.

Clearly this guy struggles away from home, and I think he is definitely due for some regression after winning three straight starts to end the month of May. Give me the Yankees to win the first five innings for us tonight.

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Nate Hornung
Nate Hornung

Nate has been a recreational sports bettor for about 5 years. In that time, he has grown to love the pursuit of winners and sticking it to The Man. Nate loves data and uses his understanding of numbers to help him be a more profitable sports gambler, however he will be the first to tell you this game is about more than just stats.

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