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Rockies

Hunter Goodman

Brett Sullivan

Braxton Fulford

Edouard Julien

Ryan Ritter

Ezequiel Tovar

TJ Rumfield

Kyle Karros

Blaine Crim

Mickey Moniak

Jake McCarthy

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Jose Quintana

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Juan Mejia

Tomoyuki Sugano

Zach Agnos

Michael Lorenzen

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Jaden Hill

Keegan Thompson

RJ Petit

McCade Brown

Pierson Ohl

Seth Halvorsen

Valente Bellozo

Tanner Gordon

Sammy Peralta

Blas Castaño

D-backs

Gabriel Moreno

James McCann

Adrian Del Castillo

Aramis Garcia

Jordan Lawlar

Tim Tawa

Nolan Arenado

Ketel Marte

Ildemaro Vargas

Geraldo Perdomo

Carlos Santana

Pavin Smith

Tyler Locklear

Jose Fernandez

Luken Baker

Jesus Valdez

Corbin Carroll

Jorge Barrosa

Alek Thomas

Lourdes Gurriel Jr.

Ryan Waldschmidt

Andrew Hoffmann

Eduardo Rodriguez

Juan Morillo

Brandon Pfaadt

Kevin Ginkel

Joe Ross

Jonathan Loáisiga

Ryne Nelson

Paul Sewald

Michael Soroka

Taylor Clarke

Zac Gallen

Ryan Thompson

Cristian Mena

Blake Walston

Merrill Kelly

Brandyn Garcia

Taylor Rashi

Philip Abner

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Colorado Rockies vs Arizona Diamondbacks Picks

Chase Field

<p>We&#8217;ve bet on tons of divisional baseball this week and it&#8217;s not stopping tonight. We head to the desert on this Thursday for a matchup between two teams in different stages of the NL West. The Arizona Diamondbacks are just five games out of first place, as they currently sit in third with their 25-23 record. At the bottom of the division is their opponent for tonight, the Colorado Rockies, who are 12 games back in the NL West with a 19-31 record. Can they turn things around? Let&#8217;s find out with our favorite MLB picks.</p>
<p>Check out the best odds on the market at <a href="/best-online-sportsbooks/">our top online sportsbooks.</a></p>
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<h2>Colorado Rockies vs. Arizona Diamondbacks MLB Betting Insights</h2>
<div id="attachment_105396" style="width: 1034px" class="wp-caption alignnone"><img loading="lazy" decoding="async" aria-describedby="caption-attachment-105396" class="size-full wp-image-105396" src="https://wp.bettingnews.com/wp-content/uploads/2026/05/hunter-goodman-colorado-rockies-mlb.jpg" alt="Hunter Goodman has 11 home runs and 19 RBIs for the Rockies this season - Rockies Diamondbacks Picks" width="1024" height="576" srcset="https://wp.bettingnews.com/wp-content/uploads/2026/05/hunter-goodman-colorado-rockies-mlb.jpg 1024w, https://wp.bettingnews.com/wp-content/uploads/2026/05/hunter-goodman-colorado-rockies-mlb-300x169.jpg 300w" sizes="auto, (max-width: 1024px) 100vw, 1024px" /><p id="caption-attachment-105396" class="wp-caption-text">Hunter Goodman has 11 home runs and 19 RBIs for the Rockies this season</p></div>
<p><a href="/mlb/matchup/2026-05-21-colorado_rockies-arizona_diamondbacks-n-1/"><button class="btn btn-block btn-primary m-2" type="button">Check out Picks and Statistics for Rockies vs. Diamondbacks here!</button></a></p>
<p>These teams already played at Coors Field earlier this month. In fact, it was just a single series ago that these two went at it in Denver. The Snakes took game one by a score of 9-1, but Colorado go their revenge by winning game two, 4-2. However, the Diamondbacks got the last laugh, winning 8-6 in game three to secure a series victory. Now the two meet again in the desert.</p>
<p>We have Zach Agnos on the bump for the Rockies, which leads me to believe we will see plenty of arms from the bullpen for the hosts. As for Arizona, they toss out Eduardo Rodriguez. The southpaw is off to a tremendous start to the year, but recently suffered his first loss of the season on Saturday, to this Rockies team. Will he be able to turn it back on at home tonight?</p>
<h3>Matchup Information &#8211; Rockies vs. Diamondbacks &#8211; May 21</h3>
<ul>
<li>Venue &amp; Location: Chase Field (Phoenix, AZ)</li>
<li>Date: Thursday, May 21, 2026</li>
<li>First Pitch: 9:40 p.m. Eastern</li>
<li>Broadcast: MLB.tv</li>
</ul>
<h3>Rockies vs. Diamondbacks Pitching Matchup</h3>
<ul>
<li>Colorado Rockies: RHP Zach Agnos (0-0, 5.59 ERA, 1.41 WHIP)</li>
<li>Arizona Diamondbacks: LHP Eduardo Rodriguez (4-1, 2.53 ERA, 1.26 WHIP)</li>
</ul>
<h3>Rockies vs. Diamondbacks Betting Odds</h3>
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<h4>Run Line</h4>
<ul>
<li>Rockies +1.5 (-112)</li>
<li>Diamondbacks -1.5 (-108)</li>
</ul>
<h4>Moneyline</h4>
<ul>
<li>Rockies +178</li>
<li>Diamondbacks -218</li>
</ul>
<h4>Total</h4>
<ul>
<li>Over 9.5 (+102)</li>
<li>Under 9.5 (-122)</li>
</ul>
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<h2>Colorado Rockies vs. Arizona Diamondbacks MLB Picks</h2>
<div id="attachment_74898" style="width: 1930px" class="wp-caption alignnone"><img loading="lazy" decoding="async" aria-describedby="caption-attachment-74898" class="size-full wp-image-74898" src="https://wp.bettingnews.com/wp-content/uploads/2025/06/2025BNMLB-Sauce.jpg" alt="Ketel Marte is hitting just .235 for the Snakes this season - Rockies Diamondbacks Picks" width="1920" height="1080" srcset="https://wp.bettingnews.com/wp-content/uploads/2025/06/2025BNMLB-Sauce.jpg 1920w, https://wp.bettingnews.com/wp-content/uploads/2025/06/2025BNMLB-Sauce-300x169.jpg 300w, https://wp.bettingnews.com/wp-content/uploads/2025/06/2025BNMLB-Sauce-1024x576.jpg 1024w" sizes="auto, (max-width: 1920px) 100vw, 1920px" /><p id="caption-attachment-74898" class="wp-caption-text">Ketel Marte is hitting just .235 for the Snakes this season</p></div>
<h3>Rockies vs. Diamondbacks Prediction: Diamondbacks Win and Cover, Over 9.5</h3>
<h3><a href="https://affiliates.bettingnews.com/register/luckyrebel-articles/" target="_blank" rel="noopener">Best Bet: Diamondbacks -1.5 (-108) Lucky Rebel Sportsbook</a></h3>
<p>Back the Diamondbacks with me. Colorado struggles to hit on the road, and slump a bit against lefties. They hit .245 as a ball club, but that drops to .236 when they are away from home, and as a team they have hit just .227 during the month of May. The Rockies have lost two straight, three of their last four, and are just 3-8 in their last 11 games overall. They continue to fall down the divisional standings, and at this point it will be tough to get themselves out of it.</p>
<p>Eduardo Rodriguez actually pitched against the Rockies on Saturday, who gave him his first loss of the year. He only allowed three earned runs in 5.1 innings, but that came off of nine total hits. However, he sat down six batters as well. Ultimately, I see him getting back to normal today.</p>
<p>Prior to that start, Rodriguez had allowed just three earned runs in his last three outings, totaling 20 innings pitched. His 2.53 ERA which is already 15th in the MLB, drops to 1.65 at home this season. And his 1.26 WHIP decreases to 0.96. The splits clearly favor him tonight, and I trust the Snakes&#8217; bats to knock around the Rockies pitchers for plenty of runs.</p>
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