Los Angeles Dodgers vs. Houston Astros Picks and Predictions: May 5, 2026
Written by: Nate Hornung
Published: Tue May 05, 2026, 10:55 am ET
Read Time: 5 minutes
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We're getting more action on the diamond tonight as the Los Angeles Dodgers find themselves in the Lone Star State facing the Houston Astros for game two of this series. After taking the first game of this series last night, the Dodgers not only extended their winning streak to two games, but they ended Houston's two game streak as well. Will they be able to rally and take tonight's contest? Find out what our analysts are wagering on by checking out their favorite picks below!
It's been a great start to the year, let's keep it up all summer long!
- MLB YTD
- 18-12 (60%)
- +6.33u
Check out the best odds on the market at our top online sportsbooks.
Los Angeles Dodgers vs. Houston Astros MLB Betting Insights
Shohei Ohtani hits .240 for the Dodgers this MLB season
The Dodgers won fairly easily last night by a score of 8-3. Tonight we get the best of both worlds as Shohei Ohtani gets the start, and likely is the designated hitter as well. The Astros are tossing out Peter Lambert who has had a rough year so far in just 15.1 innings pitched. He'll be looking to turn things around, but doing so against the Dodgers could be asking too much of the right hander.
Ohtani has been a stud on the mound and decent at the plate so far. He is hitting .240 for the Dodgers with six home runs and doubles, as well as 14 RBIs. The man has already been walked 26 times in just 33 games, as pitchers are more and more scared of giving him something good to hit. Let's check out the betting odds for tonight's game and find our picks!
Matchup Information – Dodgers vs. Astros – May 5
- Venue & Location: Daikin Park (Houston, TX)
- Date: Tuesday, May 5, 2026
- First Pitch: 8:10 p.m. Eastern
- Broadcast: TBS
Dodgers vs. Astros Pitching Matchup
- Los Angeles Dodgers: RHP Shohei Ohtani (2-1, 0.60 ERA, 0.87 WHIP)
- Houston Astros: RHP Peter Lambert (1-2, 3.52 ERA, 1.24 WHIP)
Dodgers vs. Astros Betting Odds
Odds are courtesy of our friends at Lucky Rebel Sportsbook, as of May 5, 2026, at 10:21 a.m. eastern. Sign up today and get a $1,250 deposit bonus as well as 50 slot spins immediately in your account and start betting at the sportsbook with the most competitive odds in the industry, and a wide variety of unique markets not offered anywhere else.
Run Line
- Dodgers -1.5 (-136)
- Astros +1.5 (+112)
Moneyline
- Dodgers -235
- Astros +188
Total
- Over 8.5 (-110)
- Under 8.5 (-110)
Los Angeles Dodgers vs. Houston Astros MLB Picks
Peter Lambert allowed four runs against the Cardinals in his only start at home this year
Dodgers vs. Astros Prediction: Dodgers Win and Cover, Over 8.5
Best Bet: Peter Lambert Over 2.5 Earned Runs Allowed (-120) Lucky Rebel Sportsbook
Back the Dodgers to get at least three runs off of Lambert early on in this game. He's coming off two decent outings, but in his only start at home, Lambert allowed four earned runs on seven hits and a walk to the St. Louis Cardinals in just five innings. Plus he faces arguably the best offense in all of baseball.
The Dodgers already hit .273 so far this season, but that increases to .275 against right handed pitching and all the way to .292 in 17 games on the road, where they are 10-7 overall. This is ultimately a terrible matchup for Lambert, who has already shown some struggles early on in the year. Last night, they scored seven runs in the first three innings of the game. Tonight the Astros' starter should be out there long enough to give up plenty of hits and runs.
Los Angeles ranks second in the National League and third in the MLB in terms of run differential this season, ranking fourth overall in total runs scored. Tonight they should have no problem putting the ball in play against Lambert and the Astros on the road.
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Nate has been a recreational sports bettor for about 5 years. In that time, he has grown to love the pursuit of winners and sticking it to The Man. Nate loves data and uses his understanding of numbers to help him be a more profitable sports gambler, however he will be the first to tell you this game is about more than just stats.
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