CBS Sports

Dratings

DunkelIndex

GameSim

OddsShark

Sports Betting Dime

Away/Home

Wins

Ov / Un

Reds

Mark Kolozsvary

Tyler Stephenson

Aramis Garcia

Chris Okey

Michael Papierski

Austin Romine

Chuckie Robinson

Jonathan India

Max Schrock

Alejo Lopez

Nick Senzel

Joey Votto

Kyle Farmer

Mike Moustakas

José Barrero

Colin Moran

Donovan Solano

Brandon Drury

JT Riddle

Matt Reynolds

Taylor Motter

Spencer Steer

Jake Fraley

TJ Friedl

Tyler Naquin

Aristides Aquino

Shogo Akiyama

Allan Cerda

Tommy Pham

Albert Almora Jr.

Ronnie Dawson

Stuart Fairchild

Mike Siani

Michael Siani

Hunter Greene

Tejay Antone

Tony Santillan

Ryan Hendrix

Tyler Mahle

Mike Minor

Daniel Duarte

Jeff Hoffman

Dauri Moreta

Riley O'Brien

Justin Wilson

Luis Castillo

Lucas Sims

Vladimir Gutierrez

Reiver Sanmartin

Luis Cessa

Art Warren

Alexis Díaz

Jared Solomon

Justin Dunn

James Marinan

Zack Godley

Hunter Strickland

Buck Farmer

Nick Lodolo

Phillip Diehl

Connor Overton

Robert Dugger

Joel Kuhnel

Ross Detwiler

Graham Ashcraft

Ian Gibaut

T.J. Zeuch

Chase Anderson

Derek Law

Fernando Cruz

Luke Farrell

Raynel Espinal

Kyle Dowdy

Cardinals

Ali Sánchez

Andrew Knizner

Yadier Molina

Iván Herrera

Nolan Arenado

Edmundo Sosa

Paul DeJong

Paul Goldschmidt

Tommy Edman

Brendan Donovan

Juan Yepez

Albert Pujols

Kramer Robertson

Nolan Gorman

Cory Spangenberg

Alec Burleson

Dylan Carlson

Lars Nootbaar

Tyler O'Neill

Harrison Bader

Corey Dickerson

Conner Capel

Ben DeLuzio

Steven Matz

Angel Rondón

Alex Reyes

Miles Mikolas

T.J. McFarland

Nick Wittgren

Johan Quezada

Brandon Waddell

Giovanny Gallegos

Dakota Hudson

Jack Flaherty

Kodi Whitley

Jake Walsh

Adam Wainwright

Johan Oviedo

Ryan Helsley

Jake Woodford

Freddy Pacheco

Drew VerHagen

Jordan Hicks

Génesis Cabrera

Junior Fernández

Packy Naughton

Aaron Brooks

Andre Pallante

Matthew Liberatore

Zack Thompson

James Naile

Jose Quintana

Chris Stratton

Jordan Montgomery

JoJo Romero

Away/Home Defense

Away/Home Offense

Defense

Offense

Cincinnati Reds vs St. Louis Cardinals Picks

Busch Stadium

<p>One of MLB’s elder statesmen and one of its hottest young prospects take center stage in St. Louis on Saturday afternoon as Adam Wainwright and the Cardinals take on Hunter Greene and the Cincinnati Reds. </p>
<p>Last night, the Cardinals shook off a three-game sweep against the Rays by shutting out the Reds 2-0. 23-year-old righty Andre Pallante, making just his second MLB start, more than held his own opposite Reds ace Luis Castillo, tossing 5.1 shutout innings.</p>
<p>Today, 40-year-old Wainwright, making his 370th MLB start, will look to secure the series win for the Cardinals, while 22-year-old Greene will be aiming to follow up a gem against the Arizona Diamondbacks with his second straight win in his 12th MLB start.</p>
<h2 id="22lo5">Cincinnati Reds vs. St. Louis Cardinals Betting Odds and Matchup Information</h2>
<h3 id="ccut7">Matchup Information</h3>
<ul>
<li>Matchup: Cincinnati Reds (20-38, 8-21 road, 5th in the NL Central) vs. St. Louis Cardinals (33-26, 17-11 home, 1st in the NL Central)</li>
<li>Venue &amp; Location: Busch Stadium (St. Louis, Missouri)</li>
<li>Date: Saturday, June 11, 2022</li>
<li>Time: 2:15 p.m. Eastern Time (1:15 p.m. local time)</li>
<li>How to Watch Today’s Reds vs. Cardinals Game: Bally Sports Ohio (Reds), Bally Sports Midwest (Cardinals), MLB Extra Innings/MLB.TV (subscription packages)</li>
</ul>
<h3 id="chfvk">Reds vs. Cardinals Pitching Matchup</h3>
<ul>
<li>Cincinnati Reds: Hunter Greene (2022: 11 starts, 3-7, 5.40 ERA)</li>
<li>St. Louis Cardinals: Adam Wainwright (2022: 11 starts, 5-4, 2.73 ERA)</li>
</ul>
<h3 id="c1p8b">Reds vs. Cardinals Odds</h3>
<p><strong><em>Game odds are via <a href="https://affiliates.bettingnews.com/register/betonline/" target="_blank" rel="noopener noreferrer">BetOnline</a>. Odds from our other top reviewed and recommended <a href="/best-online-sportsbooks/" target="_blank" rel="noopener noreferrer">online sportsbooks</a> may also be included in this article.</em></strong></p>
<h4 id="f9mg7">Moneyline</h4>
<ul>
<li>Cincinnati Reds +152</li>
<li>St. Louis Cardinals -180</li>
</ul>
<h4 id="ckdc6">Over/Under</h4>
<ul>
<li>OVER 8 (-120)</li>
<li>UNDER 8 (-102)</li>
</ul>
<h4 id="fqbb1">Run Line</h4>
<ul>
<li>Cincinnati Reds +1.5 (-137)</li>
<li>St. Louis Cardinals -1.5 (+114)</li>
</ul>
<h2 id="d3uiu">Can Cincinnati Have Wainwright’s Number Yet Again?</h2>
<p>In his long, successful MLB career, Wainwright has a winning record against the Chicago Cubs, Milwaukee Brewers, and Pittsburgh Pirates.</p>
<p>However, the same success has eluded him against Cincinnati, for whatever reason. In fact, of the 16 teams against whom Wainwright has logged at least ten regular season starts, he has a losing record against only the Reds. </p>
<p>In 37 career appearances against the Reds (32 starts), Wainwright is 10-16 with a 5.34 ERA. Even more astoundingly is the fact that he has been most successful in Cincinnati, where he is 7-7 with a 5.43 ERA in 21 appearances (19 starts). In 16 appearances (13 starts) in St. Louis, Wainwright is 3-9 with a 5.22 ERA.</p>
<p>His most recent win against Cincinnati was in Cincinnati on August 16, 2019, and his most recent home win against the Reds was on September 27, 2016. In his lone start against them this season, he took the loss on the road on April 24, allowing four runs, eight hits, and three walks in five innings in a 4-1 loss. </p>
<p>So, it’s safe to say that he is up against some pretty unpleasant history here. </p>
<p>But if there is something to be encouraged by, it is that he is pitching well going into today’s matchup. Since that defeat, he has six quality starts in seven starts. In that stretch, he is 3-2 with a 2.20 ERA, and has allowed just 12 runs (11 earned) in 45 innings. </p>
<h2 id="1t6n5">Reds vs. Cardinals Prediction and Best Bets</h2>
<p><strong>Reds vs. Cardinals Prediction:</strong> Cardinals to win</p>
<p><strong>Reds vs. Cardinals Best Bets:</strong> Cardinals -1.5 (+125 at <a href="https://affiliates.bettingnews.com/register/bovada/" target="_blank" rel="noopener noreferrer">Bovada Sportsbook</a>, <a href="https://affiliates.bettingnews.com/register/betus/" target="_blank" rel="noopener noreferrer">BetUS</a> &amp; <a href="https://affiliates.bettingnews.com/register/mybookie/" target="_blank" rel="noopener noreferrer">MyBookie</a>)</p>
<p>In his first start against the Cardinals, Greene allowed three runs in 3.1 innings in a 4-2 loss on April 22. He was still very much finding his feet then, but with more starts, he has begun to show why he is expected to do big things in the big leagues.</p>
<p>Greene is coming off of a seven-inning complete game in which he shut out the Arizona Diamondbacks and allowed only one hit and struck out eight (with no walks).</p>
<p>The magic number today for St. Louis might be three. Only once thus far this season have the Cardinals been held to fewer than three runs in three consecutive games. So, the odds are high that they will be able to tally at least three runs today after managing only one and two in their previous two games. </p>
<p>And if they can score even just three runs, that might be enough to get the win. When the Cardinals have scored three or more runs this season, they are 29-10, and that includes a 7-1 mark in games that Wainwright has started. And in his career, Wainwright is 171-40 in 269 starts in which St. Louis has scored three or more runs. </p>
<p>By contrast, the Reds are 2-7 in the nine Greene starts in which they have allowed three or more runs. </p>
<p>With the ML a bit out of reach with regards to value, the run line is where to turn to find value with the home team. Only seven of the Cardinals’ 33 wins this season have come by one run, including just three of their 17 home wins. </p>
<h2 id="bij8v">Other MLB Content Today on Betting News (Saturday, June 11)</h2>
<ul>
<li><a href="/articles/mlb/rangers-vs-white-sox-prediction-best-bets-june-11-2022/">Rangers vs. White Sox Prediction and Best Bets for 6/11</a></li>
</ul>
<p><script>if(window.strchfSettings === undefined) window.strchfSettings = {};window.strchfSettings.stats = {url: "https://betting-news.storychief.io/en/reds-vs-cardinals-prediction-best-bets-june-11-2022?id=1264553993&type=2",title: "Reds vs. Cardinals (June 11): Wainwright seeks 1st win vs. Cincinnati in almost three years",id: "4af471aa-0a59-40f0-a023-eeb51e59464b"};(function(d, s, id) {var js, sjs = d.getElementsByTagName(s)[0];if (d.getElementById(id)) {window.strchf.update(); return;}js = d.createElement(s); js.id = id;js.src = "https://d37oebn0w9ir6a.cloudfront.net/scripts/v0/strchf.js";js.async = true;sjs.parentNode.insertBefore(js, sjs);}(document, 'script', 'storychief-jssdk'))</script></p>

Reds vs. Cardinals (June 11): Wainwright seeks 1st win vs. Cincinnati in almost three years cover

Reds vs. Cardinals (June 11): Wainwright seeks 1st win vs. Cincinnati in almost three years

MLB Plays & Props for Sunday, May 3

Cleveland Guardians vs. Athletics Picks and Predictions: May 3, 2026

Get dialed into Saturday's MLB slate, with our picks, analysis and more. Our expert dishes out a pair of MLB best bets for today's slate.

MLB Best Bets for Saturday, May 2: Yearning for More Yankees

Bobby Witt and the Royals have struggled offensively on the road this year - Royals Mariners Picks

Kansas City Royals vs. Seattle Mariners Picks and Predictions: May 1, 2026

Check out where there is value to be had on the diamond on Friday night, as our MLB analyst dished out his MLB best bets, picks and analysis.

MLB Best Bets for Friday, May 1: Riding the Run Lines